ovarian cancer Essay - 478 Words

Of all gynecologic malignancies, ovarian cancer continues to have the highest mortality and is the most difficult to diagnose. In the United States female population, ovarian cancer ranks fifth in absolute mortality among cancer related deaths (13,000/yr). In most reported cases, ovarian cancer, when first diagnosed is in stages III or IV in about 60 to 70% of patients which further complicates treatment of the disease (Barber, 3). Early detection in ovarian cancer is hampered by the lack of appropriate tumor markers and clinically, most patients fail to develop significant symptoms until they reach advanced stage disease. The characteristics of ovarian cancer have been studied in primary tumors and in established ovarian tumor†¦show more content†¦By 1939, Schiller noted a histologic similarity to mesonephric tubules and classified these tumors as quot;mesonephromas.quot; In 1944, Saphir and Lackner described two cases of quot;hypernephroid carcinoma of the ovaryquot; and proposed quot;clear cellquot; adenocarcinoma as an alternative term. Clear cell tumors of the ovary are now generally considered to be of mullerian and in the genital tract of mullerian origin. A number of examples of clear cell adenocarcinoma have been reported to arise from the epithelium of an endometriotic cyst (Yoonessi, 289). Occasionally, a renal cell carcinoma metastasizes to the ovary and may be confused with a primary clear cell adenocarcinoma. Ovarian clear cell adenocarcinoma (OCCA) has been recognized as a distinct histologic entity in the World Health Organization (WHO) classification of ovarian tumors since 1973 and is the most lethal ovarian neoplasm with an overall five year survival of only 34% (Kennedy, 342). Clear cell adenocarcinoma, like most ovarian cancers, originates from the ovarian epithelium which is a single layer of cells found on the surface of the ovary. Patients with ovarian clear cell adenocarcinoma are typically above the age of 30 with a median of 54 which is similar to that of ovarian epithelial cancer in general. OCCA represents approximately 6% of ovarian cancers and bilateral ovarian involvement occurs in less that 50% of patients even in advanced cases. The association ofShow MoreRelatedBreast Cancer : Ovarian Cancer1359 Words   |  6 PagesOvarian cancer occurs in the ovaries but is hard to detect when the cancer is still in the first stage. There are many ways of treatment to cure ovarian cancer but is also costly. AJ is a young women who have ovarian cancer. She will undergo tests if she is positive for ovarian cancer. Survival rate are high so AJ might have a chance to be a survivor of ovarian cancer just like her mom. In this case will showing how a young girl found out that she have ovarian cancer and the treatments that sheRead MoreOvarian Cancer Essay1173 Words   |  5 PagesOne woman’s story that saved her from ovarian cancer. As a busy mother of two, working a full-time job as a primary schoolteacher, Paula Cann had plenty of reasons to ignore the subtle changes that were happening inside her body. Cann started noticed differences in urination and a small lump It began with something as simple as peeing more than usual. Cann noticed that she started having to go not only more often, but also with a new urgency. It got to the point that she could no longer enjoyRead MoreOvarian Cancer : Cancer And Cancer988 Words   |  4 Pages Ovarian cancer is a disease in which malignant or cancerous cells are found in the ovaries. The ovaries are two small organs that are located on each side of the uterus. The way cancer develops is when cells begin to grow out of control. Cancer cells are different from normal cells because they continue to grow and instead of dying, they create abnormal cells that form into a tumor. Woman around age 35-74, ovarian cancer is the fifth leading cause of death. The earlier this cancer is treatedRead MoreOvarian Cancer : Cancer And Cancer1577 Words   |  7 PagesOvarian cancer is also one of the cancer that is affecting millions of women in today’s world. The previous researches were claiming that ovarian c ancer comes from ovary cells. However, studies have found that ovarian cancer could be coming from fallopian tube. Dr. Burdette’s lab researched how fallopian tube can be contributing to ovarian cancer, and her research shows strong evidence of how does it occurs. It is very important to find a cure for ovarian cancer, otherwise deaths due to ovarian cancerRead MoreOvarian Cancer What is Ovarian Cancer? Ovarian cancer is the abnormal growth of malignant cells900 Words   |  4 PagesOvarian Cancer What is Ovarian Cancer? Ovarian cancer is the abnormal growth of malignant cells in the ovaries, the egg (ovum) producing part of the female reproductive system. Often, Ovarian cancer goes undetected until it has metastasized (spread) to the pelvis and abdomen. At this late stage, this cancer is difficult to treat. Ovarian Cancer ranks as the 11th most common cancer among women, and it is the 5th leading cause of cancer-related death for women. What different types of ovarian cancersRead MoreOvarian Cancer Case Study966 Words   |  4 PagesQuestion #1 The first primary genetic consideration is that the risk for ovarian cancer is 8%-24% for women with a BRCA mutation. This also implies that any child a woman with this mutation has, will have a 50% chance of inheriting the BRCA gene because they are autosomal dominant genes. (Norris, Spelic, Snyder, Tinley, 2009, p. 73) A second primary genetic consideration is that BRCA genes are autosomal dominant genes, which means that these genes are equally likely to be passed on to a femaleRead MoreOvarian Cancer : Development, Symptoms, Diagnosis And Treatment2191 Words   |  9 PagesOvarian Cancer: Development, symptoms, diagnosis and treatment. Ovarian cancer is the rapid and unregulated division of the ovarian cells and is referred to as the ‘most lethal gynaecologic cancer’ (1). Despite a small lifelong risk of only 1.3% in the general population and only a small proportion of 1.3% of all new cancers, ovarian cancer is the fifth-leading cause of cancer-related death in women (2). This essay will give an insight into the development of this type of cancer, the symptoms, diagnosisRead MoreThe Mortality Rate Of Ovarian Cancer1512 Words   |  7 Pagessystem. Ovarian cancer is located in the ovaries where uncontrollable multiplication of cancer cells occur (Garnick, 2014). Ovarian cancer is the fifth leading cause of death in women in the United States (Su, 2013). There are over 200,000 new cases each year worldwide and it is common in women over the age of 60 (Brain, 2014). The high mortality rate of ovarian cancer is caused by the lack of a screening techniques to detect it early on (Visintin et al, 2008). Epi thelial ovarian cancer, borderlineRead MoreOvarian Cancer : A Common Gynecological Cancer2539 Words   |  11 PagesOVARIAN CANCER by Jaymie Bailey SCIENTIFIC WRITING and CAREERS – BIOL 296 February 23, 2015 Epithelial ovarian cancer (EOC) is a common gynecological cancer that has affected many women of all ages. This disease is the leading cause of cancer related death and has killed many every year. Ovarian cancer is a disease in which cancerous tumors begin to grow in your ovaries and pelvic region and then spread further to other major organs. Fertility drugs, health habits, obesity and geneticsRead MoreTarget Therapy For Ovarian Cancer4240 Words   |  17 Pages Title: Targeted Therapy in Ovarian Cancer Authors: Hui Jun, Lim1 and William, Ledger2 Affiliations: University of New South Wales, Australia1, School of Women and Children’s Health, Prince of Wales Hospital, Sydney, Australia2 â€Æ' Abstract Among female-specific cancers worldwide, ovarian cancer is the leading cause of death from gynaecologic malignancy in the Western world. Despite radical surgery and initial high response rates to first-line chemotherapy, up to 70% of patients experience relapses